1887

Abstract

SUMMARY: Marcescin, a thermostable polypeptide isolated from a strain of inhibits the growth of at 0·01 g./ml. and at 0·1 g./ml. It is produced in good yield in 18–36 hr. at 24° in an aerated ammonium citrate glycerol medium. It was very toxic to mice and in sublethal doses failed to protect mice against sensitive organisms. It is very strongly adsorbed by bacteria so it is not possible to say whether it is bacteriostatic or bactericidal in high concentration.

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/content/journal/micro/10.1099/00221287-4-3-417
1950-09-01
2024-05-05
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References

  1. Abraham E. P., Chain E., Fletcher C. M., Gardner A. D., Heatley N. G., Jennings M. A., Florey H. W. 1941; Further observations on penicillin. Lancet ii:182
    [Google Scholar]
  2. Anker H. S., Johnson B. A., Goldberg J., Melleney F. L. 1948; Bacitracin: methods of production, concentration and partial purification, with a summary of the chemical properties of crude Bacitracin. J. Bact 55:249
    [Google Scholar]
  3. Bergey D. H. 1948 Manual of determinative bacteriology Breed R. S., Murray E. G. D., Hitchens A. P. , 6th ed.. London:: Baillière, Tindall and Cox;
    [Google Scholar]
  4. Breed R. S., Breed M. E. 1926; Serratia indica Bergey, the red chromogenic bacterium originally isolated by Koch in India. J. Bact 11:76
    [Google Scholar]
  5. Dubos R. J., Davis B. D. 1946; Factors affecting the growth of tubercle bacilli in liquid media. J. exp. Med 83:10
    [Google Scholar]
  6. Dufrenoy J., Pratt R. 1947; Cytochemical mechanisms of penicillin action.I.Oxidation-reduction levels. J. Bact 53:637
    [Google Scholar]
  7. Eisler M., Jacobbohn I. 1935; Über die antagonistisch Wirkung steriler Bouillonextracte aus Bacterium prodigiosm. Z. Hyg. InfektKr 117:76
    [Google Scholar]
  8. Elford W. J. 1931; A new series of collodion membranes suitable for general bacteriological use, especially in filterable virus studies. J. Path. Bact 34:505
    [Google Scholar]
  9. Hartwell J. L., Shear M. J., Adams J. R. 1943; Nature of the haemorrhage-producing fraction from Serratia marcescens culture filtrate. J. Nat. Cancer Inst 4:107
    [Google Scholar]
  10. Hettche H. O. 1932; Untersuchungen über die bakteriziden und anthrakoziden Bestandteil von Bacillus pyocyaneus und Bacillus prodigiosm. Arch. Hyg., Berl 107:337
    [Google Scholar]
  11. Lichstein H. C., Van der sand V. 1946; The antibiotic activity of Violacein, Prodigiosin and Phthiacol. J. Bact 52:145
    [Google Scholar]
  12. Marchal J. G., Girard T. 1947; Phénomenès d’oxydoréduction mis en evidence avec le molybdate d’ammoniaque ajouté dans les cultures bactériennes. C.R. Soc. Biol., Paris 141:118
    [Google Scholar]
  13. Pederson C. S., Breed R. S. 1928; The fermentation of glucose by organisms of the genus Serratia. J. Bact 16:163
    [Google Scholar]
  14. Reed G. B. 1937; Independent variation of several characteristics of S. marcescens. J.Bact 34:255
    [Google Scholar]
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