%0 Journal Article %A Fuller, A. T. %A Horton, Jean M. %T Marcescin, an Antibiotic Substance from Serratia marcescens %D 1950 %J Microbiology, %V 4 %N 3 %P 417-433 %@ 1465-2080 %R https://doi.org/10.1099/00221287-4-3-417 %I Microbiology Society, %X SUMMARY: Marcescin, a thermostable polypeptide isolated from a strain of Serratia marcescens inhibits the growth of Corynebacterium diphtheriae at 0·01 μg./ml. and Staphylococcus aureus at 0·1 μg./ml. It is produced in good yield in 18–36 hr. at 24° in an aerated ammonium citrate glycerol medium. It was very toxic to mice and in sublethal doses failed to protect mice against sensitive organisms. It is very strongly adsorbed by bacteria so it is not possible to say whether it is bacteriostatic or bactericidal in high concentration. %U https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-4-3-417