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Journal of Medical Microbiology logo

Volume 71, Issue 10

Technologies to decontaminate bacterial biofilm on hospital surfaces: a potential new role for cold plasma? Open Access

Abstract

Healthcare-associated infections (HCAIs) are a major challenge and the near patient surface is important in harbouring causes such as methicillin-resistant (MRSA) and . Current approaches to decontamination are sub-optimal and many studies have demonstrated that microbial causes of HCAIs may persist with onward transmission. This may be due to the capacity of these microbes to survive in biofilms on surfaces. New technologies to enhance hospital decontamination may have a role in addressing this challenge. We have reviewed current technologies such as UV light and hydrogen peroxide and also assessed the potential use of cold atmospheric pressure plasma (CAPP) in surface decontamination. The antimicrobial mechanisms of CAPP are not fully understood but the production of reactive oxygen and other species is believed to be important. CAPP systems have been shown to partially or completely remove a variety of biofilms including those caused by , and multi-drug-resistant bacteria such as MRSA. There are some studies that suggest promise for CAPP in the challenge of surface decontamination in the healthcare setting. However, further work is required to define better the mechanism of action. We need to know what surfaces are most amenable to treatment, how microbial components and the maturity of biofilms may affect successful treatment, and how would CAPP be used in the clinical setting.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): atmospheric plasma , biofilm , cleaning , cold plasma and hospital decontamination
© 2022 The Authors
  • This is an open-access article distributed under the terms of the Creative Commons Attribution NonCommercial License. This article was made open access via a Publish and Read agreement between the Microbiology Society and the corresponding author’s institution.
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2022-10-06
2024-05-02
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http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/jmm.0.001582
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Technologies to decontaminate bacterial biofilm on hospital surfaces: a potential new role for cold plasma?
J. Med. Microbiol. 71, 001582 (2022); https://doi.org/10.1099/jmm.0.001582
/content/journal/jmm/10.1099/jmm.0.001582
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