1887

Abstract

Monoclonal antibodies (MAbs) that inhibit adhesion of to human gastric cancer (MKN45) cells were established to clarify the mechanism of adhesion of Of 53 hybridoma clones screened by the primary inhibition assay for adhesion, MAb A20 of IgM class was selected on the basis of both its reactivity to whole cells of by ELISA and its inhibitory effect on adhesion of The adhesion of strain TK1029 to MKN45 cells was inhibited by MAb A20, depending on the concentration of the MAb. The MAb recognised the surface antigen, lipopolysaccharide (LPS) of , suggesting that LPS is associated with adhesion of to human gastric epithelial cells.

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1998-06-01
2022-06-29
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