1887

Abstract

Summary

The effect of gangliosides extracted from human group O Rh+ erythrocytes on haemagglutination by BK virus was investigated. Experiments were performed on both ganglioside mixtures and isolated fractions separated by column chromatography and characterized by thin-layer chromatography. These results were compared with those obtained with standard preparations of gangliosides, and the inhibiting activity was shown to be confined mainly to gangliosides with a lower than GM1. It was also observed that the insertion of gangliosides in liposomes increased the haemagglutination-inhibiting activity and that ganglioside coating restored the ability of glycosidase-treated human red blood cells to agglutinate.

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/content/journal/jgv/10.1099/0022-1317-68-3-879
1987-03-01
2019-10-13
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http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-68-3-879
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