@article{mbs:/content/journal/jgv/10.1099/0022-1317-68-3-879, author = "Sinibaldi, Laura and Viti, Donatella and Goldoni, Paola and Cavallo, Giovanni and Caroni, Cecilia and Orsi, Nicola", title = "Inhibition of BK Virus Haemagglutination by Gangliosides", journal= "Journal of General Virology", year = "1987", volume = "68", number = "3", pages = "879-883", doi = "https://doi.org/10.1099/0022-1317-68-3-879", url = "https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-68-3-879", publisher = "Microbiology Society", issn = "1465-2099", type = "Journal Article", keywords = "BK virus", keywords = "gangliosides", keywords = "haemagglutination", abstract = "SUMMARY The effect of gangliosides extracted from human group O Rh+ erythrocytes on haemagglutination by BK virus was investigated. Experiments were performed on both ganglioside mixtures and isolated fractions separated by column chromatography and characterized by thin-layer chromatography. These results were compared with those obtained with standard preparations of gangliosides, and the inhibiting activity was shown to be confined mainly to gangliosides with a R Flower than GM1. It was also observed that the insertion of gangliosides in liposomes increased the haemagglutination-inhibiting activity and that ganglioside coating restored the ability of glycosidase- treated human red blood cells to agglutinate.", }