The family includes enterically transmitted small quasi-enveloped or non-enveloped positive-sense single-stranded RNA viruses infecting mammals and birds (subfamily ) or fish (). Hepatitis E virus (genus ) is responsible for self-limiting acute hepatitis in humans; the infection may become chronic in immunocompromised individuals and extrahepatic manifestations have been described. Avian hepatitis E virus (genus ) causes hepatitis–splenomegaly syndrome in chickens. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family , which is available at www.ictv.global/report/hepeviridae.

This study was supported by the:
  • Wellcome Trust (Award WT108418AIA)
    • Principle Award Recipient: ICTVConsortium
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License.

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