RT Journal Article SR Electronic(1) A1 Sinibaldi, Laura A1 Viti, Donatella A1 Goldoni, Paola A1 Cavallo, Giovanni A1 Caroni, Cecilia A1 Orsi, NicolaYR 1987 T1 Inhibition of BK Virus Haemagglutination by Gangliosides JF Journal of General Virology, VO 68 IS 3 SP 879 OP 883 DO https://doi.org/10.1099/0022-1317-68-3-879 PB Microbiology Society, SN 1465-2099, AB SUMMARY The effect of gangliosides extracted from human group O Rh+ erythrocytes on haemagglutination by BK virus was investigated. Experiments were performed on both ganglioside mixtures and isolated fractions separated by column chromatography and characterized by thin-layer chromatography. These results were compared with those obtained with standard preparations of gangliosides, and the inhibiting activity was shown to be confined mainly to gangliosides with a R Flower than GM1. It was also observed that the insertion of gangliosides in liposomes increased the haemagglutination-inhibiting activity and that ganglioside coating restored the ability of glycosidase- treated human red blood cells to agglutinate., UL https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-68-3-879