1887

Abstract

A Gram-stain-negative, rod-shaped bacterial strain, designated IRLE0018 (=NRRL B-65642=NCTC 14661), was isolated from a cyanobacterial bloom along the Indian River Lagoon (IRL), a large and highly biodiverse estuary in eastern Florida (USA). The results of phylogenetic, biochemical, and phenotypic analyses indicate that this isolate is distinct from species of the genus with validly published names and is the closest relative to the emergent human pathogen, . Here, we present the complete genome sequence of strain IRLE0018 (4 535 135 bp). On the basis of the established average nucleotide identity (ANI) values for the determination of different species (ANI <95 %), strain IRLE0018, with an ANI of approximately 92 % compared with its closest relative, , represents a novel species within the genus . To our knowledge, this represents the first time this species has been described. The results of genomic analyses of IRLE0018 indicate the presence of antibiotic resistance genes and several known virulence factors, however, its pathogenicity profile (e.g. survival in serum, phagocytosis avoidance) reveals limited virulence potential of this species in contrast to .

Funding
This study was supported by the:
  • Burroughs Wellcome Fund (Award 1021977)
    • Principle Award Recipient: Almagro-MorenoSalvador
  • National Science Foundation (Award 2045671)
    • Principle Award Recipient: Almagro-MorenoSalvador
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2023-02-06
2024-11-06
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