Phenotypic and phylogenetic studies were performed on 15 isolates of an unidentified Gram-positive, anaerobic, non-sporulating coccobacillus-shaped bacterium isolated from human faeces. The novel organisms were catalase-negative, indole-negative and produced acetate and succinate as end products of metabolism. Comparative 16S rRNA gene sequencing demonstrated that the 15 isolates were highly related to each other and formed a hitherto unknown subline within the clostridial rRNA cluster XIVa. The novel isolates formed a robust phylogenetic group with a number of organisms which included , , and a number of other misclassified ruminococci. On the basis of these studies, a novel genus, gen. nov., is proposed. It is suggested that , , , , , and are transferred to this genus as gen. nov., comb. nov., comb. nov., comb. nov., comb. nov., comb. nov. and comb. nov. One of the new isolates, the hitherto unknown coccus-shaped bacterial strain WAL 14507 (=ATCC BAA-1564=DSM 19850) is proposed as representing the type strain of a novel species, sp. nov.


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vol. , part 8, pp. 1896 - 1902

Unrooted phylogenetic tree showing the inter-relationships of sp. nov. with some of its nearest relatives within the rRNA cluster XIVa. [ PDF] 71 KB


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