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Restriction endonuclease digestion of total purified genomic deoxyribonucleic acid gives rise to deoxyribonucleic acid fragments of discrete sizes. These can be separated by one-dimensional agarose gel electrophoresis. A unique banding pattern (fingerprint) is obtained for each actinomycete wild-type strain tested. These fingerprints are useful for recognizing a given wild-type strain and its derivatives, but cannot be used for species characterization.
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