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Microbiology Society logo Microbiology

Volume 149, Issue 9

Multilocus sequence analysis of indicates frequent recombination Free

Abstract

In this study, the genetic relationship of 19 isolates from patients with periodontitis was investigated by multilocus sequence analysis. Internal 400–600 bp DNA fragments of the 10 chromosomal genes , , , , , , , and were amplified by PCR and sequenced. No two isolates were identical at all 10 loci. Phylogenetic analyses indicated a panmictic population structure of . Split decomposition analysis, calculation of homoplasy ratios and analyses of clustered polymorphisms all indicate that recombination plays a major role in creating the genetic heterogeneity of . A standardized index of association of 0·0898 indicates that the genes analysed are close to linkage equilibrium.

  • Received:
  • Accepted:
  • Revised:
  • Published Online:
Keyword(s): , standardized index of association
SGM
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2003-09-01
2025-05-15
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/content/journal/micro/10.1099/mic.0.26267-0
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Multilocus sequence analysis of Porphyromonas gingivalis indicates frequent recombination
Microbiology 149, 2407 (2003); https://doi.org/10.1099/mic.0.26267-0
/content/journal/micro/10.1099/mic.0.26267-0
/content/journal/micro/10.1099/mic.0.26267-0
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