1887

Abstract

SUMMARY: The presence of two distinct host specificities in strain 8325 was revealed by the isolation of restriction- and modification-deficient mutants. The two host specificity systems, designated S1 and S2, are both active on phage 80 but are not additive in their restricting activity. Restriction-deficient, modification-proficient mutants were invariably affected in both restriction systems. The functional relationship between these two systems is discussed.

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1976-10-01
2022-01-28
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