1887

Abstract

SUMMARY: A new methicillin-dependent and -resistant substrain (called MRD) of was developed by serial passage followed by replica-plating. Other methicillin-resistant, but not-dependent, substrains were isolated after treatment of the same parent strain with a mutagen. A methicillin-independent partial revertant, still resistant to the drug, was isolated from the original methicillin-dependent and -resistant substrain (CRD) developed several years ago.

The requirements of some of these strains for acetate, vitamins and amino acids were compared. All except the parent methicillin-sensitive strain required pantothenate for growth, but no other consistent differences were found. The parent, but not strain , grew without lysine added to the medium, though 19 other amino acids were needed by each strain. Both of these strains fermented glucose to lactate (mainly the -isomer) in the absence or presence of methicillin.

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/content/journal/micro/10.1099/00221287-92-1-138
1976-01-01
2022-01-24
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