1887

Abstract

SUMMARY:

Forward mutations at the locus in Neurospora, and back mutations at , were scored by using the ‘suppressor method’. This method is efficient and well suited for mutagen screening. Nitrous acid, ethyl-methane sulphonate and ultraviolet radiation were effective as mutagens; 8-ethoxycaffeine yielded inconclusive results. The same pattern of forward mutations at , but different frequencies of back mutations at the locus, were obtained with the three agents. In this Neurospora system, nitrous acid appeared to induce mutations which affected simultaneously both DNA strands.

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/content/journal/micro/10.1099/00221287-30-2-317
1963-02-01
2022-05-29
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