1887

Abstract

The gene for a new bacterial aquaporin, AqpX, was cloned from the pathogenic Gram-negative bacterium . The gene was mapped on the large chromosome of . It is flanked by one upstream and two downstream copies of the repeated sequence Bru-RS. Prediction from the nucleotide sequence indicated that the protein is a member of the MIP family, which comprises channels for water and/or solute transport. Expression in oocytes and cryoelectron microscopy of cells transformed with the gene confirmed that the protein is an efficient water channel. Glycerol uptake experiments in also showed that the protein is not able to transport glycerol.

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2000-12-01
2020-11-25
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