1887

Abstract

Summary

Plasma membrane Ca-ATPase of was solubilized and partially purified by calmodulin-affinity chromatography. The activity of Ca-ATPase isolated from a cells was inhibited by physiological concentrations of the mating pheromone α-factor in a dose-dependent manner. The enzyme prepared from a receptor-deficient sterile mutant cells (Δ) was similarly inhibited by α-factor, but the enzyme from α cells was resistant to the mating pheromone. We suggest that the inhibition may be involved in the α-factor-induced increase of Ca uptake reaction of a cells.

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/content/journal/micro/10.1099/00221287-137-1-1
1991-01-01
2021-02-28
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