1887

Abstract

Summary: Nifurzide is a nitrofuran with antibacterial activity. As nitrofurans have been reported to interact with DNA, we tested the ability of nifurzide to inhibit plasmid transfer. Inhibition of plasmid transfer between strains was obtained for ten plasmids belonging to nine incompatibility groups. The same effect was observed when plasmid RP4 was harboured in six different members of the . Inhibition depended on the reduction of the -NO, group of nifurzide and was obtained with four other nitrofuran derivatives.

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/content/journal/micro/10.1099/00221287-131-9-2281
1985-09-01
2019-10-14
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http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-131-9-2281
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