RT Journal Article SR Electronic(1) A1 Michel-Briand, Y. A1 Laporte, J. M.YR 1985 T1 Inhibition of Conjugal Transfer of R Plasmids by Nitrofurans JF Microbiology, VO 131 IS 9 SP 2281 OP 2284 DO https://doi.org/10.1099/00221287-131-9-2281 PB Microbiology Society, SN 1465-2080, AB Summary: Nifurzide is a nitrofuran with antibacterial activity. As nitrofurans have been reported to interact with DNA, we tested the ability of nifurzide to inhibit plasmid transfer. Inhibition of plasmid transfer between Escherichia coli strains was obtained for ten plasmids belonging to nine incompatibility groups. The same effect was observed when plasmid RP4 was harboured in six different members of the Enterobacteriaceae. Inhibition depended on the reduction of the −NO2 group of nifurzide and was obtained with four other nitrofuran derivatives., UL https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-131-9-2281