1887

Abstract

Two independently-isolated thymine-requiring mutant strains of were found to possess an unusual phenotype: in the presence of CO, growth was independent of thymine. The two strains showed different profiles of temperature sensitivity. Glycine, serine and methionine were unable to relieve the thymine-dependence. Both strains were susceptible to trimethoprim under conditions where they were thymine-independent. The results are consistent with the occurrence of partial defects in thymidylate synthase.

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/content/journal/micro/10.1099/00221287-131-4-935
1985-04-01
2021-10-27
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