1887

Abstract

The study of strain D-2, which harbours the (ts) allele, has shown that temperature-induced filaments of this strain can divide, at 30 °C, in the absence of DNA replication and translation. Strain D-2 is thermosensitive during a period coincident with that in which the termination protein should be synthesized and exert its action. The gene product, which participates in the structure of the septum, needs for its synthesis a short period of DNA replication. The FtsA protein could be involved in a mechanism that coordinates chromosome replication and cell division by a pathway different from and independent of the SOS-induced response.

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/content/journal/micro/10.1099/00221287-131-2-239
1985-02-01
2022-01-28
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References

  1. Barbe J., Vericat J. A., Guerrero R. 1983; Discriminated induction of SOS functions in Escherichia coli by alkylating agents. Journal of General Microbiology 129:2079–2089
    [Google Scholar]
  2. Burton P., Holland I. B. 1983; Two pathways of division inhibition in UV-irradiated E. coli. Molecular and General Genetics 190:128–132
    [Google Scholar]
  3. Clark D. J. 1968; Regulation of deoxyribonucleic acid replication and cell division in Escherichia coli B/r. Journal of Bacteriology 96:1214–1224
    [Google Scholar]
  4. Clowes R. C., Hayes W. 1968 Experiments in Microbial Genetics Oxford: Blackwell Scientific Publications;
    [Google Scholar]
  5. Donachie W. D., Begg K. J., Vicente M. 1976; Cell length, cell growth and cell division. Nature, London 264:328–333
    [Google Scholar]
  6. Donachie W. D., Begg K. J., Lutkenhaus J. F., Salmond C. P. C., Martinez-Salas E., Vicente M. 1979; Role of the ftsA gene product in control of Escherichia coli cell division. Journal of Bacteriology 140:388–394
    [Google Scholar]
  7. Gottesman S., Halpern E., Trisler P. 1981; Role of-sulA and sulB in filamentation by lon mutants of Escherichia coli K-12. Journal of Bacteriology 148:265–273
    [Google Scholar]
  8. Helmstetter C. E., Pierucci O. 1968; Cell division during inhibition of DNA synthesis in Escherichia coli. Journal of Bacteriology 95:1627–1633
    [Google Scholar]
  9. Helmstetter C. E., Pierucci O., Weinberger M., Holmes M., Tang M. 1979; Control of cell division in Escherichia coli. In The Bacteria, a Treatise on Structure and Function VII517–579 Sokatch J. R., Ornston. L. N. New York: Academic Press;
    [Google Scholar]
  10. Howe W. E., Mount D. W. 1975; Production of cells without deoxyribonucleic acid during thymidine starvation of lexA cultures of Escherichia coli K-12. Journal of Bacteriology 124:1113–1121
    [Google Scholar]
  11. Howe W. E., Mount D. W. 1978; Analysis of cell division in single clones of the Escherichia coli K-12 lexA mutant. Journal of Bacteriology 133:1278–1281
    [Google Scholar]
  12. Huisman O., D’Ari R. 1981; An inducible DNA replication-cell division coupling mechanism in E. coli. Nature, London 290:797–799
    [Google Scholar]
  13. Inouye M. 1971; Pleiotropic effect of the recA gene of Escherichia coli: uncoupling of cell division from deoxyribonucleic acid replication. Journal of Bacteriology 106:539–542
    [Google Scholar]
  14. Jones N. C., Donachie W. D. 1973; Chromosome replication, transcription and control of cell division in Escherichia coli. Nature New Biology 243:100–103
    [Google Scholar]
  15. Little J. W., Mount D. W. 1982; The SOS regulatory system of Escherichia coli. Cell. 29:11–22
    [Google Scholar]
  16. Lutkenhaus J. F. 1983; Coupling of DNA replication and cell division: sulB is an allele of ftsZ. Journal of Bacteriology 154:1339–1346
    [Google Scholar]
  17. Lutkenhaus J. F., Moore B. A., Masters M., Donachie W. D. 1979; Individual proteins are synthesized continuously throughout the Escherichia coli cell cycle. Journal of Bacteriology 138:352–360
    [Google Scholar]
  18. Mizusawa S., Gottesman S. 1983; Protein degradation in Escherichia coli: the lon gene controls the stability of sulA protein. Proceedings of the National Academy of Sciences of the United States of America 80:358–362
    [Google Scholar]
  19. Schoemaker J. M., Henderson O. W., Markovitz A. 1982; Escherichia coli polypeptide controlled by the Ion (capR) ATP hydrolysis dependent protease and possibly involved in cell division. Journal of Bacteriology 152:919–923
    [Google Scholar]
  20. Tormo A., Vicente M. 1984; The ftsA gene product participates in formation of the Escherichia coli septum structure. Journal of Bacteriology 157:779–784
    [Google Scholar]
  21. Tormo A., Martinez-Salas E., Vicente M. 1980; Involvement of the ftsA gene product in late stages of the Escherichia coli cell cycle. Journal of Bacteriology 141:806–813
    [Google Scholar]
  22. Witkin E. M. 1976; Ultraviolet mutagenesis and inducible deoxyribonucleic acid repair in Escherichia coli. Bacteriological Reviews 40:869–907
    [Google Scholar]
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