1887

Abstract

Four mutants of K12 were isolated on the basis of their sensitivity to pH 5·4. Under non-permissive conditions their growth was reversibly inhibited. At pH 7·0 these mutants showed a highly pleiotropic phenotype, which included altered phage and detergent sensitivities and leakage of periplasmic proteins. The findings suggest a defect in the outer membrane, perhaps in lipopolysaccharide. Two mutants mapped in or near the locus, while the other two were remote from this region.

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/content/journal/micro/10.1099/00221287-128-8-1731
1982-08-01
2021-08-04
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