- Volume 3, Issue 3, 1970
Volume 3, Issue 3, 1970
- Articles
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Endocarditis Due to Haemophilus Parainfluenzae
More LessSUMMARYThe clinical and microbiological features of a case of subacute bacterial endocarditis due to Haemophilus parainfluenzae are described. The incidence of haemophilus endocarditis is reviewed and the treatment is discussed with special reference to the laboratory control of antibiotic therapy.
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In-Vitro Sensitivity of Shigella Sonnei to Trimethoprim and Sulphamethoxazole
More LessSUMMARYThe minimum inhibitory concentrations of trimethoprim and sulphamethoxazole were determined for 209 strains of Shigella sonnei isolated mainly in the Greater London area. All strains were sensitive to trimethoprim at a concentration of 0.32 µg per ml, but 74 per cent. of strains were resistant to sulphamethoxazole at a concentration of 100 µg per ml.
Potentiation of trimethoprim by sulphamethoxazole was demonstrated in the case of sulphonamide-sensitive strains but there was little or no potentiation in the case of sulphonamide-resistant strains.
The possible value of the combination of trimethoprim and sulphamethoxazole in the treatment of Sonne dysentery is discussed briefly.
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A Rapid and Simple Method for the Laboratory Diagnosis of Trichophyton Verrucosum
More LessSUMMARYWhen slope cultures are used to isolate fungi from dermatological specimens, the very slow growing fungus Trichophyton verrucosum cannot be identified in less than 2 wk. The use of petri-dish cultures allows direct examination of the inocula under the low power of the microscope after a brief period of incubation, when the distinctive appearance of T. verrucosum, which forms short, thick hyphae, many of which end in swollen vesicles, permits accurate reporting in 4 days. The same method allows rapid reporting of cultures on specimens that are microscopically negative and the removal of fast-growing contaminants before they obscure neighbouring inocula.
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