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Journal of Medical Microbiology logo

Volume 72, Issue 7

JMM Profile: West Nile virus Open Access

This article is part of the JMM Profiles collection.

Graphical Abstract

 Graphical abstract 

West Nile virus (WNV) is transmitted by mosquitoes in a mosquito-bird-mosquito enzootic cycle, with spillover infections in humans and horses. Created with BioRender.com.

 

Abstract

West Nile virus (WNV) is a positive-sense single-stranded RNA virus belonging to the family and is maintained in an enzootic cycle between avian hosts and mosquito vectors. Humans, horses and other mammals are susceptible to infection but are dead-end hosts due to a low viraemia. The disease can manifest itself in a variety of clinical signs and symptoms in people and horses from mild fever to severe encephalitis and morbidity. There are no vaccines licensed for human protection, but parts of Europe, North America, Africa and Australia have vaccines commercially available for horses.

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Keyword(s): Flaviviridae , mosquito-borne virus , WNV and zoonoses
Funding
This study was supported by the:
  • Animal Health and Veterinary Laboratories Agency (Award SE4116)
    • Principle Award Recipient: NotApplicable
© 2023 Crown Copyright
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License. This article was made open access via a Publish and Read agreement between the Microbiology Society and the corresponding author’s institution.
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2023-07-17
2024-05-02
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JMM Profile: West Nile virus
J. Med. Microbiol. 72, 001730 (2023); https://doi.org/10.1099/jmm.0.001730
/content/journal/jmm/10.1099/jmm.0.001730
/content/journal/jmm/10.1099/jmm.0.001730
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