1887

Abstract

SUMMARY

An in-vitro test that demonstrates adhesion of K88-positive to brush borders prepared from the small intestine of the pig is described. K88-positive adhered to the brush borders from some pigs (“positive” pigs) but not others (“negative” pigs). The sires of the pigs tested could be placed into two groups, namely, those that sired only “positive” piglets, and those that sired a mixture of “positive” and “negative” piglets. The incidence of the two phenotypes in litters indicated that “positive” and “negative” piglets arose as a result of simple Mendelian inheritance. It is suggested that “negative” pigs could be bred and that they might have a natural resistance to neonatal infection with K88-positive .

Loading

Article metrics loading...

/content/journal/jmm/10.1099/00222615-8-3-405
1975-08-01
2022-07-02
Loading full text...

Full text loading...

/deliver/fulltext/jmm/8/3/medmicro-8-3-405.html?itemId=/content/journal/jmm/10.1099/00222615-8-3-405&mimeType=html&fmt=ahah

References

  1. Arbuckle J. B. R. 1970; The location of Escherichia coli in the pig intestine. J. med. Microbiol 3:333
    [Google Scholar]
  2. Bertschinger H. U., Moon H. W., Whipp S. C. 1972; Association of Escherichia coli with the small intestinal epithelium. I. Comparison of enteropathogenic and non-enteropathogenic porcine strains in pigs. Infect. Immun 5:595
    [Google Scholar]
  3. Dixon J. M. S. 1960; The fate of bacteria in the small intestine. J. Path. Bact 79:131
    [Google Scholar]
  4. Drees D. T., Waxler G. L. 1970a; Enteric colibacillosis in gnotobiotic swine: a fluorescent microscopic study. Am. J. vet. Res 31:1147
    [Google Scholar]
  5. Drees D. T., Waxler G. L. 1970b; Enteric colibacillosis in gnotobiotic swine: an electron microscopic study. Am. J. vet. Res 31:1159
    [Google Scholar]
  6. Evans E. M., Wrigglesworth J. M., Burdett K., Pover W. F. R. 1971; Studies on epithelial cells isolated from guinea pig small intestine. J. Cell Biol 51:452
    [Google Scholar]
  7. Gibbons R. A., Jones G. W., Sellwood R. 1975; An attempt to identify the intestinal receptor for the K88 adhesin by means of a haemagglutination inhibition test using glycoproteins and fractions from sow colostrum. J. gen. Microbiol 86:228
    [Google Scholar]
  8. Jones G. W. 1972; The adhesive properties of K88-antigen of strains of Escherichia coli pathogenic to neonatal pigs. Ph.D. Thesis University of Reading;
    [Google Scholar]
  9. Jones G. W., Rutter J. M. 1972; Role of the K88 antigen in the pathogenesis of neonatal diarrhoea caused by Escherichia coli in piglets. Infect. Immun 6:918
    [Google Scholar]
  10. Jones G. W., Rutter J. M. 1974; The association of K88 antigen with haemagglutinating activity in porcine strains of Escherichia coli. J. gen. Microbiol 84:135
    [Google Scholar]
  11. Kim Y. B., Bradley S. G., Watson D. W. 1966; Ontogeny of the immune response. I. Development of immunoglobulins in germfree and conventional colostrum-deprived piglets. J. Immun 97:52
    [Google Scholar]
  12. Kohler E. M. 1968; Enterotoxic activity of filtrates of Escherichia coli in young pigs. Am. J. vet. Res 29:2263
    [Google Scholar]
  13. Miller D., Crane R. K. 1961; The digestive function of the epithelium of the small intestine. II. Localization of disaccharide hydrolysis in the isolated brush border portion of intestinal epithelial cells. Biochim. biophys. acta 52:293
    [Google Scholar]
  14. Ørskov I., Orskov F., Sojka W. J., Leach J. M. 1961; Simultaneous occurrence of Escherichia coli B and L antigens in strains from diseased swine. Acta path, microbiol. scand 53:404
    [Google Scholar]
  15. Porter P. 1969; Transfer of immunoglobulins IgG, IgA and IgM to lacteal secretions in the parturient sow and their absorption by the neonatal piglet. Biochim. biophys. acta 181:381
    [Google Scholar]
  16. Rutter J. M., Anderson J. C. 1972; Experimental neonatal diarrhoea caused by an enteropathogenic strain of Escherichia coli in piglets: a study of the disease and the effect of vaccinating the dam. J. med. Microbiol 5:197
    [Google Scholar]
  17. Smith H. W., Gyles C. L. 1970; The relationship between two apparently different enterotoxins produced by enteropathogenic strains of Escherichia coli of porcine origin. J. med. Microbiol 3:387
    [Google Scholar]
  18. Smith H. W., Jones J. E. T. 1963; Observations on the alimentary tract and its bacterial flora in healthy and diseased pigs. J. Path. Bact 86:387
    [Google Scholar]
  19. Smith H. W., Linggood M. A. 1971; Observations on the pathogenic properties of the K88, Hly and Ent plasmids of Escherichia coli with particular reference to porcine diarrhoea. J. med. Microbiol 4:467
    [Google Scholar]
  20. Sojka W. J. 1965; Escherichia coli in domestic animals and poultry. Review Series no. 7 Commonwealth Bureau of Animal Health, Farnham Royal;
  21. Sterzl J., Rejnik J., Travnicek J. 1966; Impermeability of pig placenta for antibodies. Folia microbiol II:7
    [Google Scholar]
  22. Stirm S., Ørskov F., Ørskov I., Birch-Andersen A. 1967; Episome carried surface antigen K88 of Escherichia coli. HI. Morphology. J. Bact 93:740
    [Google Scholar]
  23. Sweeney E. J. 1968; Escherichia coli in enteric disease of swine: observations on herd resistance. Ir. Vet. J 22:42
    [Google Scholar]
  24. Wijeratne W. V. S., Crossman P. J., Gould C. M. 1970; Evidence of sire effect on piglet mortality. Br. Vet. J 126:94
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-8-3-405
Loading
/content/journal/jmm/10.1099/00222615-8-3-405
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error