1887

Abstract

SUMMARY

Since 1-hydroxyphenazine derived from or chemically synthesised inhibited the uptake of oxygen by mouse liver mitochondria utilising sodium succinate, attempts were made to determine the site of activity in the electron transport chain. It was found that inhibition occurred at a site corresponding to ubiquinone (coenzyme Q) or Co Q-cytochrome ; the 1-hydroxyphenazine might act as an “ electron shunt” by accepting electrons and transporting them to a “ dead end ”.

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/content/journal/jmm/10.1099/00222615-4-2-263
1971-05-01
2022-08-14
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