1887

Abstract

Summary

Pefloxacin and fleroxacin showed biphasic bactericidal activity against KL16 in nutrient broth. Bacteriostatic concentrations of chloramphenicol, an inhibitor of protein synthesis, and rifampicin, an inhibitor of RNA synthesis, could not completely abolish the bactericidal activity of either drug. Pefloxacin and fleroxacin were also active against non-dividing KL16. There fore, pefloxacin and fleroxacin are able to kill bacteria which are not dividing nor actively synthesising protein or RNA.

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1990-06-01
2022-01-21
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