Chemotaxis of polymorphonuclear leukocytes (PMNL) in response to cell components of alone or in combination with was evaluated. produced much more powerful chemotactic factors than The culture filtrate (CF), outer membrane (OM) preparation, and lipopolysaccharide (LPS) of slightly stimulated chemotactic activity of PMNL. The culture filtrate and OM preparation were capable of inhibiting the chemotaxis of PMNL in response to the chemotactic factors of but LPS of was not able to do so. Reduction by B. fragilis of PMNL chemotaxis in response to was not specific for but also occurred in the presence of facultative bacteria. In parallel with chemotaxis, lysozyme release, but not β-glucuronidase release, by PMNL was significantly stimulated by but not by


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