@article{mbs:/content/journal/jmm/10.1099/00222615-24-2-119, author = "Namavar, F. and Vught, A. M. J.J. Verweij-Van and Bal, M. and Maclaren, D. M.", title = "Effect of Bacteroides fragilis cellular components on chemotactic activity of polymorphonuclear leukocytes towards Escherichia coli", journal= "Journal of Medical Microbiology", year = "1987", volume = "24", number = "2", pages = "119-124", doi = "https://doi.org/10.1099/00222615-24-2-119", url = "https://www.microbiologyresearch.org/content/journal/jmm/10.1099/00222615-24-2-119", publisher = "Microbiology Society", issn = "1473-5644", type = "Journal Article", abstract = "Summary. Chemotaxis of polymorphonuclear leukocytes (PMNL) in response to cell components of Bacteroides fragilis alone or in combination with Escherichia coli was evaluated. E. coli produced much more powerful chemotactic factors than B. fragilis. The culture filtrate (CF), outer membrane (OM) preparation, and lipopolysaccharide (LPS) of B. fragilis slightly stimulated chemotactic activity of PMNL. The culture filtrate and OM preparation were capable of inhibiting the chemotaxis of PMNL in response to the chemotactic factors of E. coli but LPS of B. fragilis was not able to do so. Reduction by B. fragilis of PMNL chemotaxis in response to E. coli was not specific for B. fragilis but also occurred in the presence of facultative bacteria. In parallel with chemotaxis, lysozyme release, but not β-glucuronidase release, by PMNL was significantly stimulated by E. coli but not by B. fragilis.", }