1887

Abstract

Summary

Subcutaneous injection of microgram quantities of purified SV40 DNA into newborn Syrian hamsters induced sarcomas. The tumour cells contained SV40 T-antigen and virus could be rescued from the cultured tumour cells. Addition of poly-L-ornithine or calf thymus DNA to the injection mixture did not enhance the tumour incidence. SV40 DNA cleaved with endonuclease EcoRI also displayed oncogenic potential.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-37-3-635
1977-12-01
2019-11-22
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-37-3-635
Loading

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error