@article{mbs:/content/journal/jgv/10.1099/0022-1317-37-3-635, author = "Sol, C. J. A. and van der Noordaa, J.", title = "Oncogenicity of SV40 DNA in the Syrian Hamster", journal= "Journal of General Virology", year = "1977", volume = "37", number = "3", pages = "635-638", doi = "https://doi.org/10.1099/0022-1317-37-3-635", url = "https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-37-3-635", publisher = "Microbiology Society", issn = "1465-2099", type = "Journal Article", abstract = "SUMMARY Subcutaneous injection of microgram quantities of purified SV40 DNA into newborn Syrian hamsters induced sarcomas. The tumour cells contained SV40 T-antigen and virus could be rescued from the cultured tumour cells. Addition of poly-L-ornithine or calf thymus DNA to the injection mixture did not enhance the tumour incidence. SV40 DNA cleaved with endonuclease EcoRI also displayed oncogenic potential.", }