RT Journal Article SR Electronic(1) A1 Sol, C. J. A. A1 van der Noordaa, J.YR 1977 T1 Oncogenicity of SV40 DNA in the Syrian Hamster JF Journal of General Virology, VO 37 IS 3 SP 635 OP 638 DO https://doi.org/10.1099/0022-1317-37-3-635 PB Microbiology Society, SN 1465-2099, AB SUMMARY Subcutaneous injection of microgram quantities of purified SV40 DNA into newborn Syrian hamsters induced sarcomas. The tumour cells contained SV40 T-antigen and virus could be rescued from the cultured tumour cells. Addition of poly-L-ornithine or calf thymus DNA to the injection mixture did not enhance the tumour incidence. SV40 DNA cleaved with endonuclease EcoRI also displayed oncogenic potential., UL https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-37-3-635