1887

Abstract

SUMMARY

A cross-neutralization study of 22 alphaviruses disclosed two major antigenic complexes and two viruses that were distinct from all the others. Cross-reactions were common but were restricted within the complexes. Sub-groupings within a complex were also shown, and some viruses proved to be indistinguishable by neutralization testing. The results generally paralleled previously reported data. Investigations were carried out, using BHK 21 cells in a micro tissue-culture system, on all available alphaviruses.

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1976-08-01
2024-12-07
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References

  1. BERGE T. O. 1975; International Catalogue of Arboviruses, including certain other viruses of vertebrates. U.S. Department of Health Education and Welfare Publication No. (CDC) 75-8301 789
    [Google Scholar]
  2. BURGESS G. W. 1974; A microtitre serum neutralization test for bovine ephemeral fever virus. Ajebak 52:851–855
    [Google Scholar]
  3. KARABATSOS V. 1975; Antigenic relationships of group A arboviruses by plaque reduction neutralization testing. The American Journal of Tropical Medicine and Hygiene 24:527–532
    [Google Scholar]
  4. KARABATSOS V., BUCKLEY S. M. 1967; Susceptibility of the baby-hamster kidney-cell line (BHK-21) to infection with arboviruses. The American Journal of Tropical Medicine and Hygiene 16:99–105
    [Google Scholar]
  5. LEIBOVITZ A. 1963; The growth and maintenance of tissue cell cultures in free gas exchange with the atmosphere. The American Journal of Hygiene 78:173
    [Google Scholar]
  6. PORTERFIELD J. S. 1961; Cross-neutralization studies with group A arthropod-borne viruses. The Bulletin of the World Health Organisation 34:735–741
    [Google Scholar]
  7. PUDNEY M., VARMA M. G. R., LEAKE C. J. 1973; Establishment of a cell line (XTC-2) from the S. African clawed toad. Xenopus laevis. Experientia 29:466–467
    [Google Scholar]
  8. REED L. J., MUENCH H. 1938; A simple method of estimating fifty per cent end-points. The American Journal of Hygiene 27:493–497
    [Google Scholar]
  9. SUKHAVACHANA P., YUILL T. M., RUSSELL P. K. 1969; Assay of arbovirus neutralizing antibody by micro methods. Transactions of the Royal Society of Tropical Medicine and Hygiene 63:446–455
    [Google Scholar]
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