1887

Abstract

Summary

Additional antigenic sites, distinct from those present on spherical 20 nm diam. particles of hepatitis B surface antigen (HBAg), are exposed on the surface of Dane particles and tubular forms of HBAg. The immunological relationship of these sites to e-antigen, an antigen detected earlier in HBAg-positive sera from patients with chronic hepatitis, cirrhosis or acute hepatitis but not in healthy HBAg-carriers, was established by immune electron microscopy and affinity chromatography. These findings suggest that e-antigen may be potentially useful in active immunization against hepatitis B.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-30-3-277
1976-03-01
2019-11-16
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-30-3-277
Loading

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error