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Volume 170, Issue 3

Microbe Profile: : living the sweet life via biomass break-down Open Access

This article is part of the Microbe Profiles collection.

Graphical Abstract

 Graphical abstract 

Transmission Election Microscopy (TEM) image of from a Hitachi HT7800 set to 100kV and stained with NanoW. The scalebar depicts 1µm. The polysaccharide diagrams shown are examples of substrates that the bacterium is adept at degrading. possesses an impressive array of carbohydrate active enzymes to cleave the glycosidic bonds of many plant, animal, and fungal polysaccharides.

 

 

Abstract

is a saprophytic bacterium proficient at environmental polysaccharide degradation for carbon and energy acquisition. Genetic, enzymatic, and structural characterization of carbohydrate active enzymes, specifically those that degrade plant and animal-derived polysaccharides, demonstrated that this bacterium is a carbohydrate-bioconversion specialist. Structural analyses of these enzymes identified highly specialized carbohydrate binding modules that facilitate activity. Steady progress has been made in developing genetic tools for to better understand the function and regulation of the polysaccharide-degrading enzymes it possesses, as well as to develop it as a biotechnology platform to produce renewable fuels and chemicals.

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Keyword(s): biotechnology , carbohydrate active enzyme , Cellvibrio japonicus , polysaccharide degradation and saprophyte
Funding
This study was supported by the:
  • National Institute of General Medical Sciences (Award R01GM147142-01)
    • Principle Award Recipient: JeffreyGardner
© 2024 The Authors
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License.
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2024-04-03
2024-04-29
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