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Microbial Primer: LuxR-LuxI Quorum Sensing
This article is part of the Microbial Primers collection.
Abstract
Quorum sensing is a term describing bacterial cell-to-cell communication systems for monitoring and responding to changes in population density. This primer serves as an introduction to the canonical LuxR-LuxI-type quorum sensing circuits common to many species of Gram-negative bacteria. Quorum sensing can synchronize behaviours across a community. Different species employ quorum sensing strategies to control specific behaviours such as bioluminescence, virulence factor production, secondary metabolite production, and biofilm formation.
- Received:
- Accepted:
- Published Online:
Keyword(s):
quorum sensing
Funding
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National Science Foundation
(Award 2003721)
- Principle Award Recipient: StephenP Diggle
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Division of Intramural Research, National Institute of Allergy and Infectious Diseases
(Award R01AI153116)
- Principle Award Recipient: StephenP Diggle
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Cystic Fibrosis Foundation
(Award DIGGLE20G0)
- Principle Award Recipient: StephenP Diggle