1887

Abstract

SUMMARY: DL-Norvaline inhibits growth of wild-type A number of mutants resistant to growth inhibition by this analogue were isolated and studied. Cross-feeding experiments and paper chromatography of culture supernatants indicated that the mutants excreted leucine and possibly valine and glutamate. Enzymic analysis indicated that the mutants were derepressed for acetohydroxy-acid synthetase and α-isopropylmalate synthetase; however, no derepression of threonine deaminase, dihydroxyacid dehydrase or transaminase B was observed.

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/content/journal/micro/10.1099/00221287-88-2-289
1975-06-01
2019-10-22
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http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-88-2-289
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