1887

Abstract

SUMMARY: Keto acids and free amino acids were assayed in the cells and the medium of B growing in the presence of chloramphenicol, cycloserines, aminooxyacetate, and limiting nitrogen source.

Under these growth-limiting conditions the cells accumulated ketoglutarate and ‘ketovaline’ but no other keto acids. In all experiments only ketoglutarate, pyruvate, and ‘ketovaline’ were found in the medium. Amino acids are released into the medium in the early phases of growth and the composition of the extracellular amino acids is similar to that of the amino acid pool. The concentrations of free amino acids were 10-10 times higher in the cell than in the medium. The internal pool composition is fixed under all growth-limiting conditions. In the presence of the drugs the cells release amino acids into the medium.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-87-1-141
1975-03-01
2019-10-19
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-87-1-141
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error