SUMMARY: R906, a plasmid derived from a wild strain of , was transferred to 12. In this host it is stably heritable, replicating as a DNA molecule with a molecular weight of 34.6 megadaltons. There are approximately three copies of the plasmid per chromosome. It is a member of compatibility group P. In , 906 confers resistance to ampicillin, streptomycin, sulphonamides and mercury salts. Resistance to ampicillin is determined by an oxacillin-hydrolysing β-lactamase whereas the resistance to streptomycin is not determined by either of the previously described streptomycin-inactivating enzymes but by some other mechanism.


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