1887

Abstract

Summary: Lysogenization experiments showed that diphtheria phages can induce the production of diphtheria toxin in strains of and

In addition to diphtheria toxin, lysogenic and strains each produce their own specific toxin; they also maintain their specific morphology and urease production whilst strains lysogenized by phages produce only diphtheria toxin. The majority of phages are unable to induce the production of diphtheria toxin in strains of

Phage typing with phages is a practical possibility. Thirteen well-defined phage types were established by this technique in 172 and 62 strains with only one of the phage types (III C) occurring in both species. can be distinguished from by the pathogenicity test in mice. kills mice by any route of inoculation whilst strains cause only arthritis. wild strains could be identified in this way and and strains from different type culture collections could be distinguished from each other by these well-defined characteristics.

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1974-05-01
2021-07-26
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References

  1. Afnan M. 1969; Hemolysis activity of Corynebacterium ovis. Veterinary Recorder 84:563
    [Google Scholar]
  2. Battey Y. M., Tonge J. I., Horsfall W. R., McDonald I. R. 1968; Human infection with Corynebacterium ovis. Medical Journal of Australia 2:540–543
    [Google Scholar]
  3. Barksdale L. 1970; Corynebacterium diphtheriae and its relatives. Bacteriological Reviews 34:378–422
    [Google Scholar]
  4. Calalb G., Stănică E., Maximescu P., Stoian C., Stoian I. 1965; Toxigénèse chez Corynebacterium diphtheriae mise en évidence par la méthode des cultures de tissus. Archives roumaines de pathologie expérimental et de microbiologie 24:71–76
    [Google Scholar]
  5. Carne H. R. 1968; Action of bacteriophages obtained from Corynebacterium diphtheriae on C.ulceransand C.ovis. Nature; London: 2171066–1067
    [Google Scholar]
  6. Fraser D. T. 1931; A technique for quantitative determination of diphtheria antitoxin in rabbits. Transactions of the Royal Society of Canada (S 5) 25:175–181
    [Google Scholar]
  7. Henriksen S. D. 1955; Some bacteriophages of C. ulcerans and their lack of effect on toxigenicity. Acta pathologica et microbiologica scandinavica 37:65–70
    [Google Scholar]
  8. Howard D. H., Jann G. H. 1954; The isolation and characterization of bacteriophage active against the diphtheria-like Corynebacteria. Journal of Bacteriology 68:316–319
    [Google Scholar]
  9. Jebb W.H.H. 1948; Starch-fermenting gelatin liquefying Corynebacterium isolated from human nose and throat. Journal of Pathology and Bacteriology 60:403–412
    [Google Scholar]
  10. Jebb W.H.H., Martin T. D. 1965; A non-starch-fermenting variant of C. ulcerans. Journal of Clinical Pathology 18:757–758
    [Google Scholar]
  11. Maximescu P. 1967 Corynebacterium ulcerans. Microbiologia, Parazitologia, Epidemiologia (Bucharest) 12:355–360
    [Google Scholar]
  12. Maximescu P. 1968; New host-strains for the lysogenic Corynebacterium diphtheriae Park Williams no. 8 strain. Journal of General Microbiology 53:125–133
    [Google Scholar]
  13. Maximescu P., Drăgoi T. 1971; Examen in vitro de la toxigénicité de Corynebacterium diphtheriae.Nouvelle modification du test d’Elek-Ouchterlony. Archives roumaines de pathologie expérimentale et de microbiologie 30:493
    [Google Scholar]
  14. Maximescu P., Pop A., Oprisan A., Potorac E. 1968; Relations biologiques entre C.ulcerans, C. oviset C.diphtheriae. Étude expérimentale. Archives roumaines de pathologie expérimentale et de microbiologie 27:733–750
    [Google Scholar]
  15. Narbutovicz B. 1955; Studies on the variability of C.diphtheriae induced by phage. Acta microbiologica polonica 4:245–264
    [Google Scholar]
  16. Saragea A., Maximescu P. 1964; Schéma provisoire de lysotypie chez C.diphtheriae. Archives roumaines de pathologie expérimentale et de microbiologie 23:817–838
    [Google Scholar]
  17. Stănică E., Maximescu P., Stoian C., Pop A., Oprisan R., Potorac E. 1968; Niveau de l’immunité antitoxique et le portage de bacilles diphtériques chez les chevaux dans le stade de diminution de la morbidity par la diphterie. Archives roumaines de pathologie expérimentale et de microbiologie 27:555–562
    [Google Scholar]
  18. Zaki M. M. 1966; The ability of C.ovis to produce suppurative osteomyelitis and arthritis in white mice. Journal of Comparative Pathology 76:121–126
    [Google Scholar]
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