Summary: In the conversion of quinate and shikimate to protocatechuate is catalysed by three inducible enzymes. Previous studies have demonstrated that the locus encodes a multimeric regulatory protein which is required for the synthesis of the three catabolic enzymes. The locus has been shown to encode catabolic dehydroquinase. This work defines two new classes of mutants. The locus is the structural gene for a bifunctional enzyme which catalyses the dehydrogenation of quinate and shikimate. Mutants of the class specifically lack 5-dehydroshikimate dehydrase. Alleles of the four different qa mutant classes are tightly clustered and are located to the left of in L.G. VII.


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