1887

Abstract

Summary: It is suggested that wild strain DU4916 of harbours at least two plasmids. One of them is responsible for penicillinase production and resistance to metallic ions and the other for methicillin and cephalothin resistance together with enterotoxin B production. These properties were eliminated with acridines as well as separately at different rates. Transductions were performed to restore the eliminated characters with typing phages 29 and 88. Recombination of the markers for penicillinase production and methicillin resistance on the transduced fragment seems advantageous for selection of methicillin resistance.

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1973-05-01
2021-07-23
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References

  1. Al Salihy S. M., James A. M. 1972; Loss of methicillin-resistance from resistant strains of Staphylococcus aureus . Lancet i:331–332
    [Google Scholar]
  2. Annear D. I. 1968; Effect of temperature on resistance of Staphylococcus aureus to methicillin and some other antibiotics. Medical Journal of Australia i:444–446
    [Google Scholar]
  3. Asheshov E. 1966; Chromosomal location of the genetic elements controlling penicillinase production in a strain of Staphylococcus aureus . Nature, London 210:804–806
    [Google Scholar]
  4. Asheshov E. 1969; The genetics of penicillinase production in Staphylococcus aureus strain ps 80. Journal of General Microbiology 59:289–301
    [Google Scholar]
  5. Barber M., Waterworth B. P. 1964; Penicillinase-resistant penicillins and cephalosporins. British Medical Journal ii:344–349
    [Google Scholar]
  6. Blair J. E., Williams R. E. O. 1961; Phage typing of Staphylococci. Bulletin of the World Health Organization 24:771–784
    [Google Scholar]
  7. Bouanchaud D. H., Scarizzi M. R., Chabbert Y. A. 1969; Elimination by ethidium-bromide of antibiotic resistance in enterobacteria and staphylococci. Journal of General Microbiology 54:417–425
    [Google Scholar]
  8. Chabbert Y. A., Baudens J. G., Gerbaud G. R. 1964; Variations sous l’influence de l’acriflavine et transduction de la résistance à la kanamycine et au chloramphenicol chez les Staphylococques. Annales de l’Institut Pasteur 107:678–690
    [Google Scholar]
  9. Cohen S., Sweeney H. M. 1970; Transduction of methicillin resistance in Staphylococcus aureus dependent on an unusual specificity of the recipient strain. Journal of Bacteriology 104:1158–1167
    [Google Scholar]
  10. Di Salvo J. W. 1958; Deoxyribonuclease and coagulase activity of micrococci. U.S. Armed Forces Medical Journal of Medicine and Technology Bulletin 9:191–196
    [Google Scholar]
  11. Dornbusch K., Hallander H. O., Löfquist F. 1969; Extrachromosomal control of methicillin resistance and toxin production in Staphylococcus aureus . Journal of Bacteriology 98:351–358
    [Google Scholar]
  12. Dyke K. G. H. 1969; Penicillinase production and intrinsic resistance to penicillins in methicillin-resistant cultures of Staphylococcus aureus . Journal of Medical Microbiology 2:261–278
    [Google Scholar]
  13. Dyke K. G. H., Jevons M. P., Parker M. T. 1966; Penicillinase production and intrinsic resistance to penicillins in Staphylococcus aureus . Lancet i:835–838
    [Google Scholar]
  14. Ericsson H. 1960; Rational use of antibiotics in hospitals. Scandinavian Journal of Clinical and Laboratory Investigation 12:Suppl.50
    [Google Scholar]
  15. Fairbrother R. W., Parker L., Eaton R. B. 1954; The stability of penicillinase-producing strains of Staphylococcus aureus . Journal of General Microbiology 10:309–316
    [Google Scholar]
  16. Hallander H. O. 1965; Production of large quantities of enterotoxin B and other staphylococcal toxins on solid media. Acta pathologica et microbiologica scandinavica 63:299–305
    [Google Scholar]
  17. Hallander H. O., Bengtsson S. 1967; Studies on the cell toxicity and species specificity of purified staphylococcal toxins. Acta pathologica et microbiologica scandinavica 63:107–119
    [Google Scholar]
  18. Hallander H. O., Laurell G., Dornbusch K. 1969; Determination of methicillin resistance of Staphylococcus aureus. Heterogeneity and its influence on the disc diffusion method. Scandinavian Journal of Infectious Diseases 1:169–174
    [Google Scholar]
  19. Hashimoto H., Kono K., Mitsuhashi S. 1964; Elimination of penicillin resistance of Staphylococcus aureus by treatment with acriflavine. Journal of Bacteriology 88:261–262
    [Google Scholar]
  20. Hewitt J. H., Coe A. W., Parker M. T. 1969; The detection of methicillin resistance in Staphylococcus aureus . Journal of Medical Microbiology 2:443–456
    [Google Scholar]
  21. Hewitt J. H., Parker M. T. 1968; Sensitivity of penicillinase-forming strains of Staphylococcus aureus and of their penicillinase-negative variants to cephaloridine, cephalothin, methicillin and benzyl-penicillin. Journal of Clinical Pathology 21:75–84
    [Google Scholar]
  22. Kjems E. 1955; Studies on streptococcal bacteriophages. Acta pathologica et microbiologica scandinavica 36:433–440
    [Google Scholar]
  23. May J. M., Houghton R. H., Perret C. J. 1964; The effect of growth at elevated temperatures on some heritable properties of Staphylococcus aureus . Journal of General Microbiology 37:157–169
    [Google Scholar]
  24. Mitsuhashi S., Morimura M., Kono K., Oshima H. 1963; Elimination of drug resistance of Staphylococcus aureus by treatment with acriflavine. Journal of Bacteriology 86:162–164
    [Google Scholar]
  25. Moore B. 1960; A new screen test and selective medium for the rapid detection of epidemic strains of Staphylococcus aureus . Lancet ii:453–458
    [Google Scholar]
  26. Novick R. P. 1963; Analysis by transduction of mutations affecting penicillinase formation in Staphylococcus aureus . Journal of General Microbiology 33:121–136
    [Google Scholar]
  27. Novick R. P. 1967; Penicillinase plasmids of Staphylococcus aureus . Federation Proceedings 27:29–38
    [Google Scholar]
  28. Novick R. P. 1969; Extrachromosomal inheritance in bacteria. Bacteriological Reviews 33:210–263
    [Google Scholar]
  29. Richmond M. H. 1968; The plasmids of Staphylococcus aureus and their relation to other extrachromosomal elements in bacteria. In Advances in Microbial Physiology vol 2 pp 43–38 Edited by Rose A. H., Wilkinson J. F. New York and London: Academic Press;
    [Google Scholar]
  30. Richmond M. H., John M. 1964; Co-transduction by a staphylococcal phage of the genes responsible for penicillinase synthesis and resistance to mercury salts. Nature, London 202:1360–1361
    [Google Scholar]
  31. Richmond M. H., Parker M. T., Jevons M. P., John M. 1964; High penicillinase production correlated with multiple antibiotic resistance in Staphylococcus aureus . Lancet i:293–296
    [Google Scholar]
  32. Rountree P. M. 1959; Changes in the phage-typing patterns of staphylococci following lysogenization. Journal of General Microbiology 20:620–633
    [Google Scholar]
  33. Serwin-Massieu M. 1961; Spontaneous appearance of sectored colonies in Staphylococcus aureus cultures. Journal of Bacteriology 82:316–317
    [Google Scholar]
  34. Swanstrom M., Adams M. H. 1951; Method for production of high titer phage stocks. Proceedings of the Society for Experimental Biology and Medicine 78:372–375
    [Google Scholar]
  35. Weaver J. R., Pattee P. A. 1964; Inducible resistance to erythromycin in Staphylococcus aureus . Journal of Bacteriology 88:574–580
    [Google Scholar]
  36. Wood W. B., Henninger Melva. 1969; Attachment of tail fibers in bacteriophage T4 assembly: Some properties of the reaction in vitro and its genetic control. Journal of Molecular Biology 39:603–618
    [Google Scholar]
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