SUMMARY: Encapsulated coagulase-positive staphylococci which do not clump with fibrinogen possess the clumping factor antigen as well as other cell-wall antigens characteristic of Variants which were negative for both coagulase and clumping factor not only lacked the clumping factor antigen but also other surface antigens. L-forms did not remove clumping inhibiting antibody from antisera. Antisera which were relatively high in clumping-inhibiting antibodies, but low in agglutinins, gave no fluorescence with coagulase-negative, clumping factor-negative variants or L-forms. The clumping factor, probably a cell-wall component of is absent in the penicillin-induced, stable L-form.


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