Full text loading...
Abstract
SUMMARY: Enzymes elaborated by Clostridium histolyticum and by Cl. welchii type A that disintegrated the organic component of human tooth dentine were compared with those attacking muscle collagen.
The potency of specific antisera to neutralize the enzymes disintegrating the organic component of dentine was determined by using as indicator finely divided decalcified dentine suspended in an agar gel.
By comparing the potency values of the sera with those obtained when muscle collagen preparations were used as indicators, it was evident that the organic component of dentine was attacked by the collagenases of Cl. welchii type A (κ antigen) and Cl. histolyticum (β antigen) and probably by the γ antigen of Cl. histolyticum. The λ antigen of Cl. welchii type B had no action on decalcified dentine.
- Received:
- Published Online: