SUMMARY: A comparative survey of amino acid, amino sugar, sugar and lipid components of the cell walls of strains of and was made. The cell walls of and , against which ethylenediaminetetra-acetic acid (EDTA) has a potent bactericidal action, differed from those of the other organisms principally in their sugar components and in their high content of phosphorus. EDTA at alkaline pH selectively solubilized a high proportion of the carbohydrate and phosphorus present, apparently as lipopolysaccharides, in the walls of sensitive organisms. It is suggested that metal cations and lipopolysaccharides in the cell walls of and may be essential to the structural integrity of these organisms.


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