SUMMARY Vitamin B is an essential nutrient for the flagellate when growing in axenic culture and apparently can be replaced only by a few related ‘incomplete’ analogues, i.e. only those devoid of one or both benzimidazole-methyl groups; and, of the substituted analogues, some (e.g. the mono-acid, the dicarboxylic acid and the ethylamide of B) can replace vitamin B, but some others of this group, e.g. pseudovitamin B, 2-methylmercaptoadenine cobamide, the ethylamide mono-acid, methylamide and anilide of the vitamin B, act as competitive inhibitors of the growth of


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