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SUMMARY: The effect of thirty-seven different steroids on the growth of Trichophyton rubrum is reported. The effects varied from complete inhibition of growth to stimulation. Highly inhibitory compounds included androstan-3, 17-dione, testosterone, 11-deoxycorticosterone, progesterone and 7-dehydro-cholesterol. 17α-Hydroxypregnenolone was stimulatory but all other compounds with the 17α-hydroxyl group were inactive. Structural requirements for activity are discussed.
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