1887

Abstract

SUMMARY: A procedure is given for the detection of imidazole compounds accumulated in the mycelium of adenine mutants of Of five such compounds detected, four have been tentatively identified. The distribution of these imidazoles among the mutants investigated allows a correlation between the adenine loci and the steps of purine biosynthesis.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-25-1-41
1961-05-01
2024-12-05
Loading full text...

Full text loading...

/deliver/fulltext/micro/25/1/mic-25-1-41.html?itemId=/content/journal/micro/10.1099/00221287-25-1-41&mimeType=html&fmt=ahah

References

  1. Allen R. J. L. 1940; The estimation of phosphorus. Biochem. J 34:858
    [Google Scholar]
  2. Ames B. N., Mitchell H. K. 1952; The chromatography of imidazoles. J. Amer. chem. Soc 74:252
    [Google Scholar]
  3. Barratt R. W., Newmeyer D., Perkins D. D., Garnjobst L. 1954; Map construction in Neurospora crassa . Advanc. Genet 6:1
    [Google Scholar]
  4. Beadle G. W., Tatum E. L. 1945; Neurospora II. Methods of producing and detecting mutations concerned with nutritional requirements. Amer. J. Bot 32:678
    [Google Scholar]
  5. Bratton A. C., Marshall E. K. 1939; A new coupling component for sulfanilamide determination. J. biol. Chem 128:537
    [Google Scholar]
  6. Buchanan J. M. 1958–59; The enzymatic synthesis of purine nucleotides. Harvey Lect 54:104
    [Google Scholar]
  7. Giles N. H., Partridge C. W. H., Nelson N. J. 1957; The genetic control of adenylo- succinase in Neurospora crassa . Proc. nat. Acad. Sci., Wash 43:305
    [Google Scholar]
  8. Gots J. S., Gollub E. G. 1957; Sequential blockade in adenine biosynthesis by genetic loss of an apparent bifunctionaldeacylase. Proc. nat. Acad. Sci., Wash 43:826
    [Google Scholar]
  9. Horowitz N. H. 1947; Methionine synthesis in Neurospora. The isolation of cysta-thionine. J. biol. Chem 171:255
    [Google Scholar]
  10. Lukens L. N., Buchanan J. M. 1959a; Biosynthesis of the purines. XXIII. The enzymatic synthesis of N-(5-amino-1-ribosyl-4-imidazolecarbonyl)-l-aspartic acid 5′-phosphate. J. biol. Chem 234:1791
    [Google Scholar]
  11. Lukens L. N., Buchanan J. M. 1959b; Biosynthesis of purines. XXIV. The enzymatic synthesis of 5-amino-1-ribosyl-4-imidazolecarboxylic acid 5′-phosphate from 5-amino-1-ribosylimidazole 5-phosphate and carbon dioxide. J. biol. Chem 234:1799
    [Google Scholar]
  12. Mejbaum W. 1939; Über die Bestimmungkleiner Pentosemengen, inbesondere in Derivaten der Adenylsäure. Z. physiol. Chem 258:117
    [Google Scholar]
  13. Mitchell H. K., Houlahan M. B. 1946; Adenine requiring mutants of Neurospora crassa . Fed. Proc 5:370
    [Google Scholar]
  14. Thompson A. R. 1955; Amino acid sequence in lysozyme; 2. Elution chromatography of peptides on ion-exchange resins. Biochem. J 61:253
    [Google Scholar]
/content/journal/micro/10.1099/00221287-25-1-41
Loading
/content/journal/micro/10.1099/00221287-25-1-41
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error