1887

Abstract

SUMMARY: A large collection of strains of human origin was examined for ability to inhibit the growth of on the surface of solid media. Inhibition with the formation of a sharply-defined zone was produced by members of Type 71, by certain closely-related strains, and by very few others. A small number of strains gave a wider hazy zone of inhibition. Both types of zone were produced by agents which diffused through agar, but not through cellophan, and killed . The two sorts of agent differed in their spectrum of activity for other corynebacteria. Strains of which produced sharp zones of inhibition of also had a weak inhibitory activity against strains of which were non-inhibitors or producers of hazy zones, but not on others which produced sharp zones. Ability to give rise to hazy zones persisted indefinitely in culture, but ability to produce sharp zones was regularly lost in culture after a few months. Loss of activity was accompanied by a widening of the susceptibility of the staphylococci to lysis by typing phages.

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1959-10-01
2024-12-14
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References

  1. Abbott J. D., Shannon R. 1958; A method for typing Shigella sonnet using colicine production as a marker. J. clin. Path 11:71
    [Google Scholar]
  2. Anderson E. S., Williams R. E. O. 1956; Bacteriophage typing of enteric pathogens and staphylococci and its use in epidemiology. J. clin. Path 9:94
    [Google Scholar]
  3. Dujardin-Beaumetz E. 1932; Action antibiotique d’unevariété de staphy-locoque a l’égard des bacilles Gram-positifs et acido-résistants. C.R. Soc. Biol., Paris 110:1210
    [Google Scholar]
  4. Duliscouët R. 1935; Action probiotique et antibiotique des staphylocoques chez les porteurs des germesdiphtériques. C.R. Soc. Biol., Paris 118:1277
    [Google Scholar]
  5. Duliscouët R. 1939; Recherches experimentales sur une substance bactériolytique dérivée des germes antagonistes. Les applications dans la thérapeutique de la diphtérie. Arch. Méd. Pharm. Nav 129:410
    [Google Scholar]
  6. Duliscouët R. 1945; Un antagoniste microbien nouveau. La staphyline anti-diphtérique. Pr. méd 53:653
    [Google Scholar]
  7. Fredericq P. 1946; Sur la sensibilité et l’activitéantibiotique des staphylocoques. C.R. Soc. Biol., Paris 140:1167
    [Google Scholar]
  8. Fredericq P. 1948; Actions antibiotiques réciproques chez les Enterobacteriaceae . Rev. Beige Path 19: Supp. IV
    [Google Scholar]
  9. Fredericq P., Betz-Bareau M., Nicolle P. 1956; Typage des souches d’Escherichia coli de gastro-entérite infantile par recherche de leurspropriétés colicinogènes. C.R. Soc. Biol., Paris 150:2039
    [Google Scholar]
  10. Goebel W. F., Barry G. T., Jesaitis M. A., Miller E. M. 1955; Colicine K. Nature; Lond: 176700
    [Google Scholar]
  11. Gratia A. 1925; Sur un remarquable exemple d’antagonisme entre deuxsouches de colibacille. C.R. Soc. Biol., Paris 93:1040
    [Google Scholar]
  12. Gratia A. 1946; Techniques sélectives pour la recherchesystématique des germesantibiotiques. C.R. Soc. Biol. Paris 140:1053
    [Google Scholar]
  13. Halbert S. P., Swick L., Sonn C. 1953; Characteristics of antibiotic-producing strains of the ocular bacterial flora. J. Immunol 70:400
    [Google Scholar]
  14. Hamon Y. 1956; Contribution a l’étude des pyocines. Ann. Inst. Pasteur 91:82
    [Google Scholar]
  15. Jennings M. A., Sharp A. E. 1947; Antibacterial activity of the staphylococcus. Nature; Lond: 159133
    [Google Scholar]
  16. Parker M. T. 1958; Some cultural characteristics of Staphylococcus aureus strains from superficial skin infections. J. Hyg., Camb 56:238
    [Google Scholar]
  17. Parker M. T., Tomlinson A. J. H., Williams R. E. O. 1955; Impetigo contagiosa. The association of certain types of Staphylococcus aureus and of Streptococcus pyogenes with superficial skin infections. J. Hyg., Camb 53:458
    [Google Scholar]
  18. Rosebury T., Gale D., Taylor D. F. 1954; An approach to the study of interactive phenomena among microorganisms indigenous to man. J. Bact 67:135
    [Google Scholar]
  19. Rountree P. M. 1956; Variations in a related series of staphylococcal bacteriophages. J. gen. Microbiol 15:266
    [Google Scholar]
  20. Shannon R. 1957; Colicine production AS A method for typing Bact. coli 055 B5. J. med. Lab. Technol 14:199
    [Google Scholar]
  21. Terrasse G., Sohier R. 1954; Recherches sur l’activité antibiotique et ‘probiotique’ de diverses Corynébactéries non pathogènes a l’égard de Coryne-bacterium diphtheriae . Ann. Inst. Pasteur 87:727
    [Google Scholar]
  22. Thibaut J. 1949; Activité antibiotique des Corynébactéries. C.R. Soc. Biol., Paris 143:1150
    [Google Scholar]
  23. Thibaut J., Fredericq P. 1956; Actions antibiotiques réciproques chez Corynebacterium diphtheriae . C.R. Soc. Biol., Paris 150:1512
    [Google Scholar]
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