Summary: The nuclear changes leading to spore formation in were investigated in 35 strains. Fusion of four chromatinic bodies into one mass and its subsequent break up into four bodies was observed. One of these became incorporated in the spore; the other three disintegrated. Some cells showed no fusion before spore formation; in these one chromatinic body was incorporated in the spore and the other three disintegrated. The percentage of cells in which fusion occurred varied with the strain. Rough colony strains showing a high incidence of fusion tended readily to throw smooth colony variants. Strains showing a low incidence of fusion were stable in this respect. The incidence of variants of other types bore no relation to the incidence of nuclear fusion in the strain.


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